Molasses Desugarization

Amalgamated Research LLC is a world leader in developing chromatographic technology to purify sugar solutions. ARi’s molasses desugarization technology uses simulated moving bed (SMB) chromatography to recover high-value sucrose from low-value sugar beet molasses, resulting in a high purity sucrose stream that can be further processed into crystalline sugar. In the same process, betaine is produced as a high-value byproduct. ARi has installed molasses SMB systems worldwide, operating at capacities of up to 750 tons per day.

ARi has developed similar SMB technology to produce liquid sugar directly from sugar beet thick juice and raw cane sugar, meeting purity, color, ash, and turbidity product specifications of bulk liquid sugar buyers. This SMB process eliminates the energy and equipment required to produce liquid sugar through crystallization and melting.


Direct Lithium Extraction

ARi has developed significant experience with the use of adsorbent-based technologies for the recovery of lithium from various brine feedstocks (commonly known as Direct Lithium Extraction, or DLE). In addition to this expertise, ARi has developed groundbreaking patent-pending technology for the use of simulated moving bed (SMB) chromatography for DLE, leading to substantial improvements in capital and operating costs for this application (including a reduction in water usage).

As a result of the highly-symmetrical nature of their design, fractal fluid distribution can be used to scale ion exchange, adsorption and industrial chromatography applications to any size. This allows our customers to scale up from pilot-scale equipment to full commercial-scale implementation (with vessels up to 20 ft in diameter or more), without any risk of reduced performance that would occur when using less-effective fluid distributors. This is of critical importance for applications operating at very large scale, such as beet molasses desugarization or direct lithium extraction (DLE).

High Fructose Syrups

ARi has extensive experience delivering industrial simulated moving bed (SMB) chromatography systems to purify fructose and glucose streams. Since installing its first SMB system for high-fructose corn syrup production in 1981, ARi has installed SMB systems for corn syrup applications worldwide. ARi’s SMB systems supply high purity streams for the production of syrups including HFS 55, HFS 90, crystalline fructose, and dextrose.


ARi have substantial expertise in the use of ion exchange chromatography to separate and purify proteins in the food, dairy and precision fermentation industries. ARi partners with customers to optimize the parameters having a critical influence on the economics of a protein separation, and to develop a customized solution that is optimized for the biomolecule of interest.

To learn more about our capabilities with protein separations, and the potential use of our patented Fractal Pack technology in this aplication, see ARi's brochure on protein separation and purification.

Specialty Sugars and Sweeteners

ARi has partnered with customers in a diverse range of industries to develop custom separation processes for various specialty sugar and sweetener solutions. ARi has used chromatography and other resin- or adsorbent-based processes to separate components in solutions containing fructose, glucose, sucrose, maltose, xylose, lactose, and other sugars.

See ARi's application note on the purification of steviol glycosides.

Biomass Hydrolysate

Fuels and chemical building blocks derived from renewable sources are currently a strong focus area for global research and development in the process and chemical industries. Partnering with numerous customers, ARi has developed extensive experience in separating various components from biomass hydrolysates using chromatography and other resin-based or adsorbent-based processes. In this industry, simulated moving bed chromatography is typically used to produce high purity streams containing various sugars, such as mannose, xylose, glucose, etc. These sugars may then either be fermented or reacted to generate a wide array of products. ARi’s separation technology has also been used to target specialty non-sugar components in biomass extract, such as inulin.

See ARi's application note on the recovery of hemicellulose derived sugar from spent sulfite liquor. 

Organic Acids

ARi has developed custom chromatography systems for the separation of various organic acids, including acetic acid, citric acid, succinic acid, lactic acid, and more. Feedstocks such as fermentation products can be separated into a high purity organic acid and an impurity stream. The organic acid can then be used as a renewable feedstock for chemical production, such as using purified lactic acid for polylactic acid (PLA) biopolymer production.

Inorganic Separations

ARi has developed and installed systems to perform various inorganic separations, including acid recovery from reactor product streams in the mining and biotechnology industries. Simulated moving bed chromatography vessels have been constructed using stainless steel, rubber-lined carbon steel, and CPVC to be resistant to acidic corrosion. Other components can be manufactured from polypropylene, stainless steel, Hastelloy, Alloy 20, or other suitable materials depending upon the chemical properties of the feed.

Cannabinoid Separations

ARi offers efficient chromatographic solutions for THC remediation and cannabinoid purification. Using SMB chromatography, ARi’s HIPERCHROM system continuously separates cannabinoids with high productivity and high recovery. The system can be easily scaled to match any production rate, and the long-lasting adsorbents allow for a low operating cost compared to traditional chromatography solutions.

For more information, see ARi's application note on cannabinoid separations.